Why the study?
Does oral ketamine facilitate induction of anesthesia without causing significant side effects in children?
Population
45 children (ASA Physical Status 1 and 2; aged 1-7 yr)
Comparison
Oral ketamine 3 mg/kg or 6 mg/kg mixed in 0.2… vs No ketamine mixed in 0.2 ml/kg cola-flavored…
Design
RCT, assigned randomly, double-blind
Follow-up
preoperatively and postoperatively
Authors
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Supports 6 mg/kg oral ketamine for reliable pediatric premedication; extends dose-response evidence from RCT.
Does oral ketamine facilitate induction of anesthesia without causing significant side effects in children?
An oral dose of 6 mg/kg ketamine provides predictable, satisfactory premedication without significant side effects in young children.
Gutstein et al. (1992) studied this question.
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