Metal‐Catalyzed Ring‐Opening of Alkylidenecyclopropanes: New Access to Building Blocks with an Acyclic Quaternary Stereogenic Center

Open sesame! A selective metal-catalyzed ring opening of alkylidenecyclopropane derivatives leads to various functionalized acyclic derivatives possessing challenging quaternary stereocenters. The key feature of this transformation is that the ring opening is faster than the reductive elimination and is highly regioselective; a single ring-opened product was always observed and the stereointegrity of the quaternary stereogenic center remains unaffected in the process.