Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
May 1, 1976Cardiovascular Research

Influence of training on myocardial responses of rats subjected to conditions of ischaemia and hypoxia

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does physical training improve cardiac performance in rats subjected to hypoxia and myocardial ischaemia?

Population

Rats subjected to acute conditions of hypoxia and myocardial ischaemia

Comparison

Physical training (running on a treadmill) vs Non-trained rats

Design

Preclinical

Authors

RCR. A. CareyCTC. M. TIPTONDLD. R. LUND

Discussion

Loading...

Member takes

Overview

Physical training improves post-hypoxic performance in rat hearts without ischaemic benefit; leaves open translation to human disease models.

Structured PICO

Does physical training improve cardiac performance in rats subjected to hypoxia and myocardial ischaemia?

P
Population
Rats subjected to acute conditions of hypoxia and myocardial ischaemia
I
Intervention
Physical training (running on a treadmill)
C
Comparator
Non-trained rats
O
Outcome
Cardiac performance (dP/dt max) after hypoxia and ischaemiasurrogate

Physical training improves cardiac performance following hypoxia but not ischaemia in a rat model, without altering myocardial oxygen utilization or energy availability.

Cite This Study

Carey et al. (1976) studied this question.

synapsesocial.com/papers/6a80b90873f13514bdeede18https://doi.org/10.1093/cvr/10.3.359
View Full Paper
Ask AI
Bookmark
Share