April 1, 1972Circulation Research

Effect of Physical Training on the Mechanical and Metabolic Response of the Rat Heart to Hypoxia

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Why the study?

Does physical conditioning by swimming improve cardiac function and metabolism during hypoxia in rats?

Population

Rats (isolated hearts)

Comparison

Physical conditioning by swimming vs Sedentary rats

Design

Preclinical

Authors

JSJames ScheuerAlbert Einstein College of Medicine SSS. William StezoskiUnited States Army Medical Command

Discussion

Member takes

Implication

Does not support clinical changes in hypoxic heart disease; hypothesis-generating for exercise preconditioning and requires human validation.

Structured PICO

Does physical conditioning by swimming improve cardiac function and metabolism during hypoxia in rats?

Population

Rats (isolated hearts)

Intervention

Physical conditioning by swimming

Comparator

Sedentary rats

Outcome

Cardiac function and metabolism during hypoxia (including cardiac output, cardiac work, systolic pressures, oxygen delivery, lactate production, and energy stores)surrogate

Physical conditioning improves the mechanical efficiency of the rat heart during hypoxia without altering oxygen delivery or energy formation.

Cite This Study

Scheuer et al. (1972) studied this question.

synapsesocial.com/papers/6a7cb5ddfecf32cfa06117c1 https://doi.org/10.1161/01.res.30.4.418

View Full Paper

Ask AI

Bookmark

Implication

Does not support clinical changes in hypoxic heart disease; hypothesis-generating for exercise preconditioning and requires human validation.

Effect of Physical Training on the Mechanical and Metabolic Response of the Rat Heart to Hypoxia

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Effect of Physical Training on the Mechanical and Metabolic Response of the Rat Heart to Hypoxia

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider