Why the study?
Does exercise training with marked reductions in exercise heart rate via atenolol enhance intrinsic myocardial performance in rats?
Population
Rats (normal-trained, atenolol-trained, and sedentary controls)
Comparison
Treadmill running at approximately 80% VO2max… vs Normal-trained rats and sedentary controls
Design
Preclinical
Follow-up
8 weeks
Authors
Loading...
Exercise training with atenolol does not augment intrinsic cardiac capacity in rats beyond normal training; leaves open human translation.
Does exercise training with marked reductions in exercise heart rate via atenolol enhance intrinsic myocardial performance in rats?
Exercise training with beta-blockade reduces exercise heart rate but does not enhance the intrinsic functional capacity of the rodent heart compared to normal training.
Mullin et al. (1984) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: