Why the study?
Does endurance training alter cardiac structure and myocardial mechanics in young and adult male rats?
Population
Young and adult male rats
Comparison
Physical training by graded treadmill running… vs Sedentary controls
Design
Preclinical
Follow-up
12 weeks
Authors
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Rodent findings warrant no change in clinical exercise advice; leaves open human cardiac remodeling with moderate endurance training.
Does endurance training alter cardiac structure and myocardial mechanics in young and adult male rats?
Moderate endurance training in rats does not cause significant cardiac hypertrophy or consistent changes in myocardial contractility, challenging some assumptions about exercise-induced cardiac remodeling.
Nutter et al. (1981) studied this question.
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