Why the study?
Does intensity-controlled endurance exercise alter the cardiac proteome in rats?
Population
Rats (n=12 total; n=6 exercised, 280 +/- 3 g; n=6 control, 330 +/- 2 g)
Comparison
Intensity-controlled endurance exercise vs Weight-matched control animals
Design
Preclinical
Follow-up
6 weeks
Authors
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Hypothesis-generating for exercise effects on cardiac proteome; leaves open translation to human outcomes or practice.
Does intensity-controlled endurance exercise alter the cardiac proteome in rats?
Intensity-controlled endurance exercise in rats induces specific cardiac proteomic adaptations, including increased expression of myofibrillar and fatty acid metabolism proteins, and novel phosphorylation of heat shock protein 20.
Jatin G. Burniston (2008) studied this question.
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