December 1, 2025Diabetes Metabolic Syndrome and ObesityOpen Access

Sex-Specific Associations Between Anthropometric Indices and Left Ventricular Hypertrophy in Middle-Aged and Elderly Individuals with Type 2 Diabetes Mellitus

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Why the study?

The associations between anthropometric indicators and left ventricular hypertrophy in middle-aged and elderly individuals with type 2 diabetes mellitus required investigation.

Do anthropometric indices predict left ventricular hypertrophy in middle-aged and elderly individuals with type 2 diabetes mellitus?

Population

3330 middle-aged and elderly individuals with T2DM across three tertiary hospitals in China

Comparison

Various anthropometric indices (BMI, WHR, WHtR, BAI, BRI, WWI) assessed for association with LVH

Design

Multicenter cross-sectional study

Authors

QTQingxiu TianNanjing University of Chinese Medicine QCQian CuiUniversity of Electronic Science and Technology of China RZRong ZhangNanjing University of Chinese Medicine

Discussion

Member takes

Implication

Should not yet change LVH screening in T2DM; leaves open sex-specific anthropometrics as risk markers pending prospective data.

Structured PICO

Do anthropometric indices predict left ventricular hypertrophy in middle-aged and elderly individuals with type 2 diabetes mellitus?

Population

3,330 individuals with type 2 diabetes mellitus (T2DM), aged 45 years or older, recruited from three tertiary hospitals in Jiangsu Province, China. Exclusions: missing covariates, absence of echocardiographic indices, severe comorbidities (malignancy, heart failure, hepatic or renal failure, chronic kidney disease, congenital heart disease, cardiomyopathy, coagulation dysfunction).

Intervention

Anthropometric indices including body mass index (BMI), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), body adiposity index (BAI), body roundness index (BRI), and weight-adjusted-waist index (WWI)

Outcome

Left ventricular hypertrophy (LVH), defined as LVMI ≥115 g/m2 in men and ≥95 g/m2 in womensurrogate

Sex-specific anthropometric indices, particularly waist-to-hip ratio in men and body adiposity index in women, are associated with left ventricular hypertrophy in middle-aged patients with type 2 diabetes.

Cite This Study

Tian et al. (2025) studied this question.

synapsesocial.com/papers/6a80c1956b002de6d43fcdac https://doi.org/10.2147/dmso.s566225

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Sex-Specific Associations Between Anthropometric Indices and Left Ventricular Hypertrophy in Middle-Aged and Elderly Individuals with Type 2 Diabetes Mellitus

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Sex-Specific Associations Between Anthropometric Indices and Left Ventricular Hypertrophy in Middle-Aged and Elderly Individuals with Type 2 Diabetes Mellitus

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider