Why the study?
Does statin therapy reduce major heart failure events in patients from primary, secondary, and mixed prevention trials?
Population
Up to 132,568 pooled participants from 17 primary, secondary, and mixed prevention trials, including ~92,600…
Comparison
Statin therapy vs Control
Design
Editorial
Follow-up
mean 4.3 years
Authors
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Although a recent meta-analysis suggests statin therapy reduces first non-fatal heart failure hospitalizations, limitations regarding unknown baseline heart failure status and statin lipophilicity prevent definitive conclusions for patients with existing heart failure.
Does statin therapy reduce major heart failure events in patients from primary, secondary, and mixed prevention trials?
Although a recent meta-analysis suggests statin therapy reduces first non-fatal heart failure hospitalizations, limitations regarding unknown baseline heart failure status and statin lipophilicity prevent definitive conclusions for patients with existing heart failure.
Westman et al. (2015) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: