Anaphylaxis is a serious allergic reaction that can be rapid in onset and occasionally fatal. This is a review of the literature on the epidemiology of anaphylaxis, diagnostic criteria, mechanisms, and management. This current review of the literature is intended for clinicians, trainees, and researchers as a comprehensive review of anaphylaxis with a focus on incorporating the latest advances in the field. Cite this as: J. K. Lee and P. Vadas, Clinical & Experimental Allergy, 2011 (41) 923–938.
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