Cerebral circulation time increases linearly with age and is altered by the presence of narcosis.
May support age-adjusted cerebral circulation references; leaves open clinical relevance and need for prospective studies.
Cerebral circulation time was studied with angiography of the carotid artery within a group of 45 normal cases of different age. The results showed an approximately linear increase of the circulation time with age, the coefficient of which amounts to 1% per year. For an average age of 35 years the average circulation time was determined and found to be 3.2 sec with narcosis and 4.3 sec without narcosis. This indicates that narcosis is another important parameter for the cerebral circulation.
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Möller et al. (2008) studied this question.
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