Case report demonstrates amphotericin B-induced thrombophlebitis during mucormycosis treatment, highlighting the critical need to monitor adverse vascular effects.
Amphotericin B is most widely used antifungal drug of choice. We report a case of a 56-year-old man developed pain and skin swelling over right forearm at the intravenous access site during amphotericin B administration treatment given for mucormycosis, the post-operative of sinuses. After 4 hours of affected period, amphotericin B was administration. A well revealed thrombophlebitis of the right forearm was noted. The systemic reaction was assessed based on the naranjo algorithm and was found to be probable. The safety profile of amphotericin B and its adverse effects must be monitored on long term treatment usage. Key words: Thrombophlebitis, Amphotericin B, Adverse drug reaction, Pharmacovigilance, Mucormycosis.
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