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March 1, 1997British Journal of HaematologyOpen Access

Dose reduction of asparaginase under pharmacokinetic and pharmacodynamic control during induction therapy in children with acute lymphoblastic leukaemia

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Authors

EAE. AhlkeKlinik und Poliklinik für Kinder- und JugendmedizinÜULRIKE NOWAK‐GO ̈TTLSociety of Paediatric Oncology and HaematologyPSP. Schulze-WesthoffTemple Street Children's University Hospital

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Ahlke et al. (1997) studied this question.

synapsesocial.com/papers/6a80d7c4762dba2aae64632ahttps://doi.org/10.1046/j.1365-2141.1997.d01-2089.x
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1L-asparaginase activity in plasma and other biological fluids1970 · 59 citations
  2. 2Levels of L-asparagine in CSF after intramuscular administration of asparaginase from Erwinia in children with acute lymphoblastic leukemia.1995 · 38 citations
  3. 3E. coli L-asparaginase in the treatment of leukemia and solid tumors in 131 children1970 · 175 citations
  4. 4Comparative pharmacokinetic studies of three asparaginase preparations.1993 · 338 citations