Why the study?
Does enoxaparin inhibit repetitive thrombus formation better than unfractionated heparin in a canine model of unstable angina?
Population
Canine model of unstable angina with experimentally induced vascular stenosis and damage causing…
Comparison
Enoxaparin administered intravenously as a… vs Unfractionated heparin administered…
Design
Preclinical
Follow-up
1 hour
Authors
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Enoxaparin may suppress repetitive thrombus formation more than heparin in this model; leaves open translation to human unstable angina.
Does enoxaparin inhibit repetitive thrombus formation better than unfractionated heparin in a canine model of unstable angina?
Enoxaparin, but not unfractionated heparin, effectively prevents repetitive platelet-dependent thrombus formation in a canine model of unstable angina.
Leadley et al. (1998) studied this question.
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