Clinical experience of pain management in infectious and inflammatory diseases of pharynx

The article presents clinical cases that focus on administration of ketoprofen as a throat wash and flurbiprofen as lozenges in a child with acute viral tonsillopharyngitis and two adult patients with peritonsillar abscesses. The drugs have been shown to provide a rapid and strong analgesic effect. Patients reported a significant reduction in pain within 10–20 minutes after administration of the drugs. It was emphasized that the combined use of a throat wash and lozenges produced a faster effect as compared to the single-drug therapy. The patient with a peritonsillar abscess who received a combination of two drugs demonstrated a complete relief of sore throat a day earlier than a patient who only received lozenges as pain relief therapy. No adverse reactions to the drugs were observed in patients. The presented cases are accompanied by a literature review, which provides information on the epidemiology, causes and mechanisms, as well as methods for treating a sore throat. Otolaryngologists most often see patients with nociceptive pain caused by an infectious and inflammatory factor in their practice. A wide range of drugs from various groups (antiseptics, antibiotics, local anesthetics, etc.) are used to relieve pain, but only a group of non-steroidal anti-inflammatory drugs has a pathogenetic effect.