Why the study?
Is epicardial fat volume associated with the presence and subtype of atrial fibrillation?
Population
Patients with atrial fibrillation and healthy participants from 7 observational case series studies.
Comparison
Atrial fibrillation (persistent or paroxysmal) vs Healthy participants or paroxysmal AF
Design
Meta-analysis
Authors
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Epicardial fat volume may identify higher AF risk and persistence; extends observational meta-analyses but leaves causal role and therapeutic targeting open.
Is epicardial fat volume associated with the presence and subtype of atrial fibrillation?
Epicardial fat volume is significantly increased in patients with atrial fibrillation, particularly in those with persistent compared to paroxysmal AF, suggesting a potential role in atrial arrhythmogenesis.
Gaeta et al. (2017) studied this question.