Key result
Young adult ischemic stroke affects predominantly men, with other determined etiologies causing ~27% of cases.
Observational (n=149)
No
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Prospective study reveals high rates of arterial atherosclerosis and male predominance in young adults with ischemic stroke, highlighting vascular risk factor exposure.
OBJECTIVES: To evaluate the characteristics of ischemic stroke in Korean young adults. MATERIAL AND METHODS: We prospectively studied 149 consecutive patients with acute ischemic stroke aged between 15 to 44 years who were admitted to Asan Medical Center. All patients underwent brain CT/MRI and the majority of them underwent cerebral anglogram, echocardiography and laboratory studies for coagulopathy and vasculitis. Stroke subtypes were classified according to TOAST criteria. RESULTS: In our study, men (75.2%) significantly outnumbered women. Stroke subtypes were: large artery atherosclerosis 20.8%), small artery occlusive disease 17.4%), cardioembolism 18.1%, undetermined causes 16.8%, and other determined etiologies 26.8%. The prevalence of hypertension, cigarette smoking and habitual alcohol consumption was significantly higher in men than in women. CONCLUSIONS: Compared to the western studies, the deviation of sex ratio and the relative proportion of large artery atherosclerosis/small artery occlusion was higher. Heavy exposure to risk factors such as hypertension and cigarette smoking in Korean young men may explain these differences.
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Kwon et al. (2000) conducted an observational in Acute ischemic stroke (n=149). Cardiovascular risk factors and sex differences in young onset stroke was evaluated on Distribution of TOAST stroke subtypes. Korean young adults with ischemic stroke were predominantly male, with 26.8% having other determined etiologies, 20.8% large artery atherosclerosis, and 18.1% cardioembolism.
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