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October 14, 1997Proceedings of the National Academy of SciencesOpen Access

Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia

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Authors

KCKathleen M. CaronSSShiu-Ching SooWWWilliam C. Wetsel

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Caron et al. (1997) studied this question.

synapsesocial.com/papers/6a8149ccd433ecbb06e1bcffhttps://doi.org/10.1073/pnas.94.21.11540
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Metabolism of Pro-Luteinizing Hormone-Releasing Hormone in Immortalized Hypothalamic Neurons*1991 · 77 citations
  2. 2Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13.1995 · 386 citations
  3. 3Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation.1995 · 952 citations
  4. 4Processing of the Luteinizing Hormone-Releasing Hormone Precursor in the Preoptic Area and Hypothalamus of the Rat1988 · 26 citations
  5. 5Steroid 5α-Reductase 2 Deficiency*1993 · 335 citations