This review summarizes the pathophysiology, diagnosis, and evolving therapeutic options for aortic stenosis, highlighting the transformative role of transcatheter aortic valve replacement.
Guides current AS management emphasizing TAVR; leaves open questions on long-term durability and lower-risk expansion.
Aortic stenosis is the most common valvular disease requiring valve replacement. Valve replacement therapies have undergone progressive evolution since the 1960s. Over the last 20 years, transcatheter aortic valve replacement has radically transformed the care of aortic stenosis, such that it is now the treatment of choice for many, particularly elderly, patients. This review provides an overview of the pathophysiology, presentation, diagnosis, indications for intervention, and current therapeutic options for aortic stenosis.
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