Key result
Transcatheter aortic valve replacement is an effective therapy for patients at high risk for surgery and has been found superior to medical therapy in inoperable patients with aortic stenosis.
Why the study?
Does transcatheter aortic valve replacement improve outcomes in patients with aortic stenosis who are at high risk for surgery or inoperable?
Does transcatheter aortic valve replacement improve outcomes in patients with aortic stenosis who are at high risk for surgery or inoperable?
Transcatheter aortic valve replacement has emerged as an effective therapy for high-risk surgical patients and is superior to medical therapy in inoperable patients with aortic stenosis.
Supports TAVR consideration in high-risk or inoperable aortic stenosis; leaves open durability and lower-risk expansion.
Aortic stenosis is the most common cause for valvular surgery in the USA. For nearly 50 years, surgical aortic valve replacement has been the standard of care for symptomatic patients; unfortunately, a significant number of patients are not referred to surgery owing to advanced comorbidities and age. Transcatheter aortic valve replacement has emerged as an effective therapy for patients at high risk for surgery. Through device innovations and accumulated experience, the safety and efficacy of the procedure has improved since its inception. Transcatheter valve replacement has been found superior to medical therapy in inoperable patients with aortic stenosis, yet many questions remain as to which patients are appropriate for this exciting and novel therapy.
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Liff et al. (2011) conducted a review in Aortic stenosis. Transcatheter aortic valve replacement vs. Surgical aortic valve replacement or medical therapy was evaluated. Transcatheter aortic valve replacement is an effective therapy for patients at high risk for surgery and has been found superior to medical therapy in inoperable patients with aortic stenosis.
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