Why the study?
How does the continuation versus discontinuation of antiplatelet therapy affect the risk of stent thrombosis, myocardial infarction, and death in patients with coronary artery stents undergoing noncardiac surgery?
Population
Patients with coronary artery stents (bare-metal or drug-eluting) undergoing noncardiac surgery
Design
Review
Authors
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Informs perioperative decisions for stented patients; leaves open need for RCTs to confirm optimal antiplatelet strategies.
How does the continuation versus discontinuation of antiplatelet therapy affect the risk of stent thrombosis, myocardial infarction, and death in patients with coronary artery stents undergoing noncardiac surgery?
This review emphasizes the critical importance of continuing aspirin perioperatively in patients with coronary stents to prevent life-threatening stent thrombosis, unless bleeding risks significantly outweigh the benefits.
Newsome et al. (2008) studied this question.
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