Why the study?
Air pollutants cause respiratory and cardiovascular morbidity and mortality, perturbing the autonomic nervous system critical to cardiopulmonary homeostasis, and understanding these mechanisms could improve management and treatment.
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Design
Review
May explain pollution-related autonomic imbalance; hypothesis-generating and requires prospective validation.
Air pollutants pose a serious worldwide health hazard, causing respiratory and cardiovascular morbidity and mortality. Pollutants perturb the autonomic nervous system, whose function is critical to cardiopulmonary homeostasis. Recent studies suggest that pollutants can stimulate defensive sensory nerves within the cardiopulmonary system, thus providing a possible mechanism for pollutant-induced autonomic dysfunction. A better understanding of the mechanisms involved would likely improve the management and treatment of pollution-related disease.
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Thomas E. Taylor‐Clark (2020) studied this question.
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