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I erated upon for benign biliary tract disease at The New York Hospital, New York, N.Y.During the same period a total of 147 cases of biliary tract carcinoma were seen (Fig. 1).or a ratio of 1 carcinoma for every 32 operations.The carcinomas included 90 cases of histologically proved carcinoma of the gallbladder, 26 cases of carcinoma of the ampulla of Vater, and 31 cases of carcinoma of the bile ducts.The age factor in the incidence of cancer as compared to benign biliary tract disease is shown in Table 1.From this table, it may be seen that carcinoma of the biliary tree is primarily a disease of persons more than 50 years of age.The incidence of carcinoma of the gallbladder as regards sex and age is shown in 'Table 2.The table indicates that cancer of this organ is seen most frequently in the seventh decade of life; 50y0 of the entire group of patients studied were between 60 and 69 years of age.T h e incidence in women is nearly 3 times
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Thorbjarnarson et al. (1959) studied this question.
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