Eosinophilic Granulomatosis with Polyangiitis Revealed by Acute Cholecystitis: A Rare Manifestation

This is the authors' abstract. We don't add key points for this paper.

Acute cholecystitis is a rare disease of eosinophilic granulomatosis with polyangiitis, which is a systemic necrotizing vasculitis affecting small- to medium-sized vessels, associated with blood and tissue eosinophilia and the presence of extravascular granulomas. We report the case of a 53-year-old female patient who presented with acute acalculous cholecystitis who underwent surgery. The diagnosis of eosinophilic granulomatosis with polyangiitis was based on histology of the gallbladder, antineutrophil cytoplasmic antibody positivity and the presence of polyneuropathy. Corticosteroids allowed a favorable clinical outcome with no relapses during follow-up.