November 1, 1986Annals of Internal Medicine
Clinically Silent Atrial Septal Defects with Evidence for Cerebral Embolization
Why the study?
Does microcavitation contrast two-dimensional echocardiography detect clinically silent atrial septal defects in young patients with cerebral embolization?
Population
11 consecutive patients, age 50 and younger, with clinical evidence of cerebral embolization and normal…
Design
Case_series
Authors
Discussion
Loading...
Member takes
Implication
May support paradoxical embolization via silent ASD in young stroke; hypothesis-generating and should not yet change practice.
Structured PICO
Does microcavitation contrast two-dimensional echocardiography detect clinically silent atrial septal defects in young patients with cerebral embolization?
P
Population
11 consecutive patients, age 50 and younger, with clinical evidence of cerebral embolization and normal physical, radiographic, electrocardiographic, and two-dimensional echocardiographic examinations.
I
Intervention
Microcavitation contrast two-dimensional echocardiography
O
Outcome
Detection of right-to-left shunts at the atrial levelsurrogate
Contrast two-dimensional echocardiography is effective in detecting clinically silent atrial septal defects in young patients with unexplained stroke, suggesting paradoxical embolization as a potential mechanism.
Cite This Study
John R Harvey (1986) studied this question.