Why the study?
Rapid deployment prostheses expand treatment to higher-risk patients with aortic stenosis, but are linked with a higher need for permanent pacemakers during the immediate postoperative period.
What is the incidence and what are the risk factors for permanent pacemaker implantation after aortic valve replacement with a rapid deployment prosthesis?
What is the incidence and what are the risk factors for permanent pacemaker implantation after aortic valve replacement with a rapid deployment prosthesis?
The incidence of permanent pacemaker implantation after aortic valve replacement with the Edwards Intuity rapid deployment prosthesis is 8%, with previous AMI and preoperative amiodarone identified as significant risk factors.
May inform targeted monitoring after rapid-deployment AVR in select patients; leaves open need for prospective validation.
BACKGROUND: Aortic stenosis is currently the most frequently occurring valve pathology. Developments, such as transcatheter prostheses and rapid deployment prostheses, allow for the offer of a valve replacement to higher risk patients, but these techniques are linked with a higher need for a permanent pacemaker during the immediate postoperative period. METHODS: We studied the incidence and the factors associated with permanent pacemaker implantation after aortic valve replacement with Edwards Intuity rapid deployment prosthesis. RESULTS: Between October 2012 and December 2016, the Edwards Intuity prosthesis was implanted in 71 patients (68% male, 75.3 ± 5 years old). Six patients (8%) required a permanent pacemaker during immediate postoperative period. Univariate analysis showed that a history of acute myocardial infarction (AMI) (P = .046, B = 7.5, 95% CI [1.039-54.1]) and preoperative amiodarone (P = .009, B = 31.5; 95% CI [2.32-426]) were associated with a higher need for a pacemaker during the postoperative period. CONCLUSIONS: The incidence of permanent pacemaker implantation during the immediate postoperative period of aortic valve replacement with Edwards Intuity prosthesis was 8%, a value which is within the limits reported for conventional aortic prostheses. Preoperative amiodarone treatment and previous AMI may increase the need for a pacemaker during the postoperative period of these aortic prostheses.
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Arribas et al. (2019) studied this question.
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