Why the study?
Does intra-aortic balloon pump (IABP) counterpulsation during reperfusion reduce the extent of myocardial infarction and no-reflow phenomenon in a pig ischemia-reperfusion model?
Population
11 pigs in an ischemia-reperfusion experimental model
Comparison
Intra-aortic balloon pump support starting 10… vs No IABP support (controls)
Design
Preclinical
Follow-up
2 hours of reperfusion
Authors
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May inform IABP timing in reperfusion; hypothesis-generating in porcine model and leaves human translation open.
Does intra-aortic balloon pump (IABP) counterpulsation during reperfusion reduce the extent of myocardial infarction and no-reflow phenomenon in a pig ischemia-reperfusion model?
In a porcine model of ischemia-reperfusion, IABP support initiated before reperfusion increased coronary blood flow and reduced infarct size and the no-reflow phenomenon.
Pierrakos et al. (2011) studied this question.
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