Why the study?
Does uterine artery Doppler index in the first trimester predict adverse pregnancy outcomes such as preeclampsia and low birth weight?
Does uterine artery Doppler index in the first trimester predict adverse pregnancy outcomes such as preeclampsia and low birth weight?
Answers are grounded in this paper and cite their sources.
Uterine artery Doppler index measured at 11-14 weeks of gestation is significantly associated with subsequent adverse pregnancy outcomes including preeclampsia and low birth weight.
In the non pregnant state and in early pregnancy, Doppler interrogation of the UtA typically demonstrates steep systolic slope early diastolic notch low end diastolic velocities. The waveforms remain essentially high resistance. UtA impedance can be affected by various factors such as maternal heart rate, antihypertensive use hormonal changes in the menstrual cycle, and chronic hyperandrogenism in the polycystic ovarian syndrome. Informed consent from each patient was obtained. Gestational age was calculated from the last menstrual period and confirmed by crown—rump length measurement. Abiding by the inclusion exclusion criteria patients were selected into the study. Clinical history including clinical risk factors to develop hypertension in pregnancy were noted, physical examination was done. The P1 doppler index showed a statistical significance for adverse outcomes like preeclampsia (p 0.002), low birth weight (LBW) (p = 0.04), and with 47 adverse outcomes (p = 0.02) from 11- 14 weeks. We had 17 cases of LBW, out of which only 4 (23.5%) were there not attributed to any complications, all the rest occurred as a part of prematurity caused by preeclampsia, fetal growth restriction (FGR) and oligoamnios.
No takes yet. Share an insight, caveat, or question.
Ravikumar et al. (2021) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: