Endothelin-1 is a potent regulator of systemic vascular resistance and capacitance, playing a major role in the pathophysiology of hypertension.
Authors
No takes yet. Share an insight, caveat, or question.
Endothelin receptor antagonism merits exploration in hypertension; leaves open confirmation of outcome benefits in randomized trials.
J. Robert McNeill (2003) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: