Why the study?
The study was conducted to test the use of the Dutch leakage score, serum C-reactive protein, and serum procalcitonin for diagnosing anastomotic leakage after elective colorectal resection.
Does the use of the Dutch leakage score, serum CRP, and serum procalcitonin accurately diagnose anastomotic leakage after elective colorectal surgery?
Population
1546 patients undergoing elective colorectal resection with anastomosis across 19 centres
Comparison
Dutch leakage score vs serum CRP vs serum PCT evaluated on POD2, POD3, and POD6
Design
Prospective multicentre observational study
Authors
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May aid exclusion of anastomotic leakage after colorectal surgery; hypothesis-generating and requires prospective validation before practice change.
Does the use of the Dutch leakage score, serum CRP, and serum procalcitonin accurately diagnose anastomotic leakage after elective colorectal surgery?
The combination of the Dutch leakage score, CRP, and procalcitonin provides excellent negative predictive value for excluding anastomotic leakage after elective colorectal surgery.
Catarci et al. (2020) studied this question.
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