Because of improvements in the technics of ureterointestinal anastomosis, cystectomy and partial cystectomy, there is need for a reevaluation of the indications and contraindications of the various types of treatment for patients with carcinoma of the bladder. A review of 540 patients with carcinoma of the bladder treated at the University Hospital from the years 1932 to 1942, a study of more recent patients treated more radically and a review of the recent literature emphasize the need for individual treatment of these patients. In order to adequately evaluate the various types of therapy, a basis of reference for classifying these tumors is necessary. This has been generally recognized. Jewett and Strong 1 have shown that the microscopic anatomic structure or grade of malignancy of an infiltrating carcinoma of the bladder reveals only the potentiality of the tumor for rapid growth and metastasis but does not, in itself, indicate the presence
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R. H. Flocks (1951) studied this question.
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