Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
March 13, 2023Open Access

Impact of initial dialysis modality on the survival of patients with ESRD: A propensity-score-matched study

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Studies comparing the survival of patients undergoing hemodialysis versus peritoneal dialysis have yielded controversial results.

Does initial peritoneal dialysis compared to hemodialysis improve survival in patients with end-stage renal disease?

Population

739 ESRD patients initiating renal replacement therapy (including 125 matched pairs)

Comparison

Initial hemodialysis vs initial peritoneal dialysis

Design

Single-center retrospective propensity-score-matched cohort study

Authors

LLLi LiuJPJie PangLLLinna Liu

Discussion

Loading...

Member takes

Overview

No survival difference between HD and PD overall; leaves open possible PD benefit in diabetics as hypothesis-generating.

Structured PICO

Does initial peritoneal dialysis compared to hemodialysis improve survival in patients with end-stage renal disease?

P
Population
739 patients with end-stage renal disease (ESRD) who initiated renal replacement treatment between January 1, 2010, and December 31, 2018, from a single center in the Chinese National Renal Data System (CNRDS). A matched cohort of 125 PD and 125 HD patients was analyzed.
I
Intervention
Peritoneal dialysis (PD) as initial dialysis modality
C
Comparator
Hemodialysis (HD) as initial dialysis modality
O
Outcome
Survival (mortality)hard clinical

Initial dialysis modality (HD vs PD) does not significantly impact overall survival in ESRD patients, though PD may offer a survival advantage in diabetic patients.

Cite This Study

Liu et al. (2023) studied this question.

synapsesocial.com/papers/6a816f390fbd199afca8cbd2https://doi.org/10.21203/rs.3.rs-2481089/v1
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of survival in patients with end-stage renal disease receiving hemodialysis versus peritoneal dialysis2015 · 22 citations
  2. 2Early Mortality Among Peritoneal Dialysis and Hemodialysis Patients Who Transitioned With an Optimal Outpatient Start2018 · 20 citations
  3. 3Mortality predictor pattern in hemodialysis and peritoneal dialysis in diabetic patients2018 · 47 citations
  4. 4Life expectancy, expected years of life lost and survival of hemodialysis and peritoneal dialysis patients2010 · 30 citations
  5. 5An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational Studies2011 · 12,423 citations