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June 1, 2001HeartOpen Access

A comparison of left ventricular abnormalities associated with glucose intolerance in African Caribbeans and Europeans in the UK

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Why the study?

Does glucose intolerance increase left ventricular mass index and alter diastolic function in African Caribbeans and Europeans?

Population

1152 African Caribbeans and Europeans in London, UK

Comparison

Glucose intolerance / diabetes vs Normoglycaemia

Design

Cross-sectional

Authors

NCNish Chaturvedi

Discussion

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Overview

Diabetes-associated LVMI elevation should not yet change practice; leaves open confounding by obesity/hypertension and ethnic differences in remodeling.

Structured PICO

Does glucose intolerance increase left ventricular mass index and alter diastolic function in African Caribbeans and Europeans?

P
Population
1152 African Caribbeans and Europeans in London, UK
I
Intervention
Glucose intolerance / diabetes
C
Comparator
Normoglycaemia
O
Outcome
Left ventricular mass index, wall thickness, and early (E) to atrial (A) wave ratiosurrogate

Left ventricular abnormalities occur in response to glucose intolerance, largely accounted for by associated obesity and hypertension, with African Caribbeans showing greater structural impairment.

Cite This Study

Nish Chaturvedi (2001) studied this question.

synapsesocial.com/papers/6a8171ae176d2ce031662498https://doi.org/10.1136/heart.85.6.643
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left Ventricular Hypertrophy in Non-insulin-dependent Diabetic Patients With and Without Diabetic Nephropathy1997 · 52 citations
  2. 2Diabetes, Other Risk Factors, and 12-Yr Cardiovascular Mortality for Men Screened in the Multiple Risk Factor Intervention Trial1993 · 4,104 citations
  3. 3Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements.1978 · 7,474 citations
  4. 4Echocardiographic evidence for the existence of a distinct diabetic cardiomyopathy (The Framingham Heart Study)1991 · 556 citations
  5. 5Left ventricular function in diabetes mellitus. I: Methodology, and prevalence and spectrum of abnormalities.1981 · 127 citations