Why the study?
Primary adrenal leiomyosarcoma is a rare mesenchymal tumor with high metastatic risk, with only roughly 40 cases previously reported.
This report adds 3 new cases to the limited literature (roughly 40 previously reported cases) on primary adrenal leiomyosarcoma, detailing its characteristics.
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Raises consideration of leiomyosarcoma in adrenal incidentalomas; leaves open optimal diagnostic strategies pending more data.
Primary adrenal leiomyosarcoma (PAL) is a rare, high-grade proliferating mesenchymal tumor with a considerable risk of metastasis, deriving from the smooth muscle wall of a central adrenal vein, or its tributaries. Roughly 40 patients with PAL have been reported in the literature. Herein, we present 3 patients with incidentally discovered PAL, along with an overview of the current knowledge on the clinical, radiological, and histopathological characteristics of PAL.
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Jabarkhel et al. (2020) studied this question.
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