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August 4, 2023CureusOpen Access

Primary adrenal lymphoma carries a poor prognosis with a ~33% two-year overall survival rate.

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Why the study?

Primary adrenal lymphoma is a rare tumor, and the study aimed to demonstrate its histopathological features at two tertiary hospitals.

Population

7 patients with primary adrenal lymphoma

Design

Retrospective study at two tertiary hospitals

Key result

Primary adrenal lymphoma is a rare disease of the elderly, predominantly diffuse large B-cell lymphoma, with a poor prognosis demonstrated by 1-year and 2-year overall survival rates of 50% and 33%, respectively.

Authors

JAJaudah Al‐Maghrabi

Discussion

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Member takes

Overview

Alerts clinicians to include primary adrenal lymphoma in elderly adrenal mass differentials; leaves optimal therapy open pending prospective data.

Study Design

Type

Observational (n=7)

Multicenter

Yes

Structured PICO

P
Population
7 patients (mean age 63.3 years, 42.9% female) diagnosed with primary adrenal lymphoma at two tertiary hospitals in Saudi Arabia between 2003 and 2023, followed for a median of 22 months.
O
Outcome
Histopathological features and overall survival

Primary adrenal lymphoma is a rare disease of the elderly, most commonly diffuse large B-cell lymphoma, and is associated with a poor prognosis.

Limitations

  • Extremely small sample size due to the rarity of the disease
  • Retrospective study design
  • Missing clinical follow-up data for one patient

Cite This Study

Jaudah Al‐Maghrabi (2023) conducted an observational in Primary Adrenal Lymphoma (n=7). Primary Adrenal Lymphoma was evaluated on 1-year and 2-year overall survival rates. Primary adrenal lymphoma is a rare disease of the elderly, predominantly diffuse large B-cell lymphoma, with a poor prognosis demonstrated by 1-year and 2-year overall survival rates of 50% and 33%, respectively.

synapsesocial.com/papers/6aa9124fd75aeabedda33bc3https://doi.org/10.7759/cureus.42940
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