Why the study?
Does direct oral anticoagulant use reduce hospital admission or emergency department visit for major bleeding and all cause mortality compared to warfarin in adults with incident venous thromboembolism?
Does direct oral anticoagulant use reduce hospital admission or emergency department visit for major bleeding and all cause mortality compared to warfarin in adults with incident venous thromboembolism?
In adults with incident venous thromboembolism, DOACs have a similar safety profile to warfarin regarding major bleeding and all-cause mortality in the first 90 days of treatment.
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Supports similar bleeding risk with DOACs versus warfarin in incident VTE; leaves open need for randomized confirmation.
Jun et al. (2017) studied this question.
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