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August 16, 2026Scientific ReportsOpen Access

Endovenous thermal ablation combined with foam sclerotherapy is a safe and effective method for the treatment of lower extremity varicose veins: a multicenter retrospective analysis

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Authors

HCHuanyu ChenWQWei QiuWLWuhao Li

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Overview

Retrospective study demonstrates reduced perioperative complications with thermal ablation over vein stripping in varicose vein patients, suggesting superior recovery with equivalent efficacy.

Key Points

  • To compare the safety, clinical efficacy, and perioperative outcomes of radiofrequency ablation and endovenous microwave ablation combined with foam sclerotherapy versus conventional high ligation and stripping for symptomatic lower extremity varicose veins.
  • Analyzed 305 patients across two clinical centers in a multicenter retrospective study.
  • Assigned participants to radiofrequency ablation plus foam sclerotherapy (n=102), endovenous microwave ablation plus foam sclerotherapy (n=101), or high ligation and stripping (n=102) with 12 months of follow-up.
  • Complication rates were lower in the radiofrequency ablation (34.3%) and microwave ablation (41.6%) groups compared to high ligation and stripping (58.8%).
  • Both thermal ablation techniques produced significantly shorter operation times, reduced blood loss, shorter hospital stays, lower postoperative pain scores, and reduced inflammatory (CRP, IL-6) and coagulation (D-dimer, fibrinogen) markers.
  • Venous Clinical Severity Scores, CIVIQ-20 quality-of-life scores, and recurrence rates showed no significant differences among the three groups at 12 months postoperatively.

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a817980f2fb91fc834aca2bhttps://doi.org/10.1038/s41598-026-66990-4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of endovascular microwave ablation and traditional vein stripping for lower extremities varicose veins: A retrospective study2025
  2. 2SP4.05 Beyond the Scalpel: Evaluating Endovenous Ablation Techniques for Varicose Vein2025
  3. 3Endovenous microwave ablation versus high ligation and stripping for the treatment of small saphenous vein incompetence. A single center retrospective study2026
  4. 4A comparative study of endovenous laser ablation and radiofrequency ablation in the management of varicose veins2025 · 1 citations
  5. 5Comparison of the safety and efficacy between endovenous laser ablation and radiofrequency ablation for great saphenous vein incompetence2025 · 2 citations