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August 16, 2026Scandinavian Journal of Primary Health CareOpen Access

Out-of-hours C-reactive protein point-of-care testing and its association with long-term healthcare-seeking

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Authors

JLJesper LykkegaardUniversity of CopenhagenJOJonas OlsenUniversity of Southern DenmarkCVClaus Høstrup VestergaardUniversity of Southern Denmark

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Implication

Cohort study reveals increased long-term out-of-hours healthcare revisits after seeing high-testing general practitioners, suggesting diagnostic testing may encourage unnecessary future visits.

Key Points

  • To evaluate whether patient exposure to general practitioners with a high frequency of C-reactive protein point-of-care testing is associated with increased long-term use of out-of-hours primary care services.
  • Conducted a register-based time-to-event study analyzing all in-person out-of-hours primary care consultations in the Central Denmark Region from 2014 to 2017 (N = 862,733).
  • Defined exposure as the general practitioner's adjusted tendency to use CRP-POCT relative to peers across their preceding 50 consultations, adjusting for patient demographics, practitioner experience, and consultation timing.
  • The overall proportion of consultations utilizing CRP-POCT increased from 12% in 2014 to 19% in 2017, with Kaplan-Meier estimates indicating a median time of 2.5 years before 50% of patients returned for another out-of-hours visit.
  • Patients treated by general practitioners with twice the average CRP-POCT usage or greater had an increased rate of revisiting out-of-hours care compared to those seen by average-use practitioners (adjusted HR = 1.038, 95% CI = 1.023 to 1.054).

Cite This Study

Lykkegaard et al. (2026) studied this question.

synapsesocial.com/papers/6a81799af2fb91fc834acc89https://doi.org/10.1080/02813432.2026.2706193
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