Seroprevalence of cytomegalovirus IgG and IgM antibodies and associated factors among women with spontaneous abortion in Lahj Governorate, Yemen

Objectives This study aimed to determine the seroprevalence of anti-CMV IgG and anti-CMV IgM antibodies among women with spontaneous abortion in Lahj Governorate, Yemen. An analytical cross-sectional study was among 110 women with spontaneous abortion. Five milliliters of blood were collected from women, sera were separated, and anti-CMV IgG and IgM were determined using a Cobas ® e 411 analyzer that is based on electrochemiluminescence immunoassay (ECLIA). The data were entered and then analyzed using SPSS. Associations were assessed using the chi-square test, and prevalence ratios (PR) with 95% confidence intervals (CIs) were calculated. Results The seroprevalence of anti-CMV IgG and IgM antibodies was 80.9% and 7.3%, respectively. A statistically significant association was observed between anti-CMV IgM seropositivity and having experienced two previous spontaneous abortions (PR = 5.0, 95% CI: 1.13–21.97; p = 0.042). A high seroprevalence of CMV IgG antibodies and low IgM seropositivity among women with spontaneous abortion in Lahj, Yemen.