Pupillary Abnormalities in Diabetic Neuropathy

Article1 November 1967Pupillary Abnormalities in Diabetic NeuropathyA Preliminary StudySANDOR A. FRIEDMAN, M.D., RICHARD FEINBERG, PH.D., EDWARD PODOLAK, M.S., ROWLAND H. S. BEDELL, M.D.SANDOR A. FRIEDMAN, M.D.Search for more papers by this author, RICHARD FEINBERG, PH.D.Search for more papers by this author, EDWARD PODOLAK, M.S.Search for more papers by this author, ROWLAND H. S. BEDELL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-67-5-977 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe frequent involvement of the autonomic nervous system in the peripheral neuropathy of diabetes mellitus can give rise to a variety of syndromes (1). Patients may manifest such diverse problems as orthostatic hypotension, impotence, neurogenic bladder, and nocturnal diarrhea (1, 2). Also attributed to autonomic neuropathy are the frequently reported abnormalities of the pupil (2). Some authors have estimated that 9% to 25% of all diabetics have clinically recognizable changes such as sluggish reaction to light, even the loss of the light reflex, and excessive miosis (1, 3). In order to study the movements of the diabetic pupil in detail...References1. MARTIN MM: Diabetic neuropathy. A clinical study of 150 cases. Brain 76: 594, 1953. CrossrefMedlineGoogle Scholar2. WILLIAMS RH: Diabetes, 1st ed. Hoeber Medical Division, Harper & Row, Inc., New York, 1960, pp. 610-612. Google Scholar3. RUNDLES RW: Diabetic neuropathy. General review with report of 125 cases. Medicine (Balt.) 24: 111, 1945. CrossrefGoogle Scholar4. COLLENSZILENSKYBOAS WSJDLC: Impaired vibratory sense in diabetes. Amer. J. Med. 1: 638, 1946. CrossrefMedlineGoogle Scholar5. STEINESS I: Vibratory perception in diabetes. Acta Med. Scand. 158: 327, 1957. CrossrefMedlineGoogle Scholar6. MIRSKYFUTTERMANBROHKAHN IAPRN: The quantitative measurement of vibratory perception in subjects with and without diabetes mellitus. J. Lab. Clin. Med 41: 221, 1953. MedlineGoogle Scholar7. KESSLER J: Personal communication of unpublished data. Google Scholar8. FEINBERGPODOLAK RE: Latency of pupillary reflex to light stimulation and its relationship to aging, in Behavior, Aging and the Nervous System, edited by WELFORD, A. T., BIRREN, J. E. Charles C Thomas, Publisher, Springfield, Ill., 1965, chap. 17. Google Scholar9. LOWENSTEINLOEWENFELD OIE: Electronic pupillography. A new instrument and some clinical applications. Arch. Ophthal. (Chicago) 59: 353, 1958. Google Scholar10. FEINBERGPODOLAK RE: Latency of pupillary reflex to light stimulation and its relationship to pupil size. Paper presented at 5th Colloquium on the Pupil, University of Pennsylvania, Philadelphia, 1967. Google Scholar11. WOLTMANWILDER HWRM: Diabetes mellitus. Pathological changes in the spinal cord and peripheral nerves. Arch. Intern. Med. (Chicago) 44: 576, 1929. CrossrefGoogle Scholar12. FAGERBERG SE: Studies on the pathogenesis of diabetic neuropathy. Survey of literature and our own working hypothesis. Acta Med. Scand. 154: 145, 1956. CrossrefMedlineGoogle Scholar13. DREYFUSHAKIMADAMS PMSRD: Diabetic ophthalmoplegia. Arch. Neurol. (Chicago) 77: 337, 1957. Google Scholar14. GILLILAND IC: Clinical syndrome associated with Kimmelstiel-Wilson lesion of kidney. Brit. Med. J. 1: 916, 1951. CrossrefMedlineGoogle Scholar15. RUDYEPSTEIN ASH: Review of one hundred cases of "diabetic neuropathy" followed from one to ten years. J. Clin. Endocr. 5: 92, 1945. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Washington, D. C.From the Federal Aviation Agency, U. S. Public Health Service, and the Georgetown University Hospital, Washington, D. C.At the time of this study Dr. Friedman was a Fellow in the Department of Cardiovascular Surgery, supported by Georgetown University Hospital, Washington, D. C.Requests for reprints should be addressed to Sandor A. Friedman, M.D., Coney Island Hospital, Ocean and Shore Parkways, Brooklyn, N. Y. 11235. 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FRIEDMAN,, M.D., F.A.C.P., PAUL FREIBERG, M.D., JAY COLTON, M.D.Recent Contributions to the Study of Diabetic Angiopathy and NeuropathyPUPILLOMOTORISCHE VERÄNDERUNGEN BEI DIABETIKERNDisorders of the Nervous System in DiabetesDiabetes and the nervous system 1 November 1967Volume 67, Issue 5Page: 977-983KeywordsBladderDiabetes mellitusDiarrheaErectile dysfunctionHypotensionMedical servicesNeuropathyPeripheral neuropathyReflexesSurgery Issue Published: 1 November 1967 PDF DownloadLoading ...