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Overlapping tryptic, peptic, thermolytic, and Pronase peptides containing 4'-phosphopantetheine were isolated from rat liver fatty acid synthetase. Characterization of these peptides and a 4'-phosphopantetheine dipeptide obtained after dilute acid hydrolysis permitted the elucidation of the amino acid sequence of 13 residues. Five out of the 13 residues are identical with those in the corresponding region of Escherichia coli acyl carrier protein.
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Roncari et al. (1972) studied this question.
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