Key result
A hemodialysis session did not significantly change mean platelet aggregation values (375.33 vs 363.01 AU × minutes; P=0.597), though aspirin resistance status changed in 16.6% of patients.
Why the study?
Does a hemodialysis session affect aspirin resistance measured by the Multiplate test in patients undergoing hemodialysis?
Population
54 patients undergoing hemodialysis
Comparison
Hemodialysis session vs Pre-hemodialysis state
Design
Cross-sectional
Follow-up
Immediate (before and after hemodialysis session)
Authors
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Individual aspirin resistance status may vary around hemodialysis; leaves open need for standardized Multiplate timing in future studies.
Observational (n=54)
Does a hemodialysis session affect aspirin resistance measured by the Multiplate test in patients undergoing hemodialysis?
Absolute Event Rate: 375.33% vs 363.01%
p-value: p=.597
While mean platelet aggregation values do not significantly change after hemodialysis, individual aspirin resistance status changes in a significant minority of patients, suggesting hemodialysis may affect antiplatelet efficacy assessment.
Aksu et al. (2013) conducted an observational in Hemodialysis (n=54). Hemodialysis vs. Before hemodialysis was evaluated on Platelet aggregation values (p=.597). A hemodialysis session did not significantly change mean platelet aggregation values (375.33 vs 363.01 AU × minutes; P=0.597), though aspirin resistance status changed in 16.6% of patients.
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