Key result
A 6-week exercise-based cardiac rehabilitation programme significantly improved 6-minute walk test distance by 15% (from 389.5 to 447.9 metres, p<0.0001) in patients with atrial fibrillation.
Why the study?
Despite increasing evidence for exercise-based cardiac rehabilitation in atrial fibrillation, the intervention has not been widely adopted within the NHS.
Does a 6-week exercise-based cardiac rehabilitation programme improve exercise capacity and psychological health in patients with symptomatic atrial fibrillation?
Observational (n=77)
No
Does a 6-week exercise-based cardiac rehabilitation programme improve exercise capacity and psychological health in patients with symptomatic atrial fibrillation?
Effect estimate: 15% improvement
Absolute Event Rate: 447.9% vs 389.5%
p-value: p=<0.0001
An established 6-week NHS exercise-based cardiac rehabilitation programme is feasible for patients with atrial fibrillation and may improve short-term exercise capacity and psychological well-being.
There is increasing evidence for the role of exercise-based cardiac rehabilitation in the management of patients with atrial fibrillation (AF). However, this intervention has not yet been widely adopted within the National Health Service (NHS). We performed a feasibility study on the utilisation of an established NHS cardiac rehabilitation programme in the management of AF, and examined the effects of this intervention on exercise capacity, weight, and psychological health. We then identified factors that might prevent patients from enrolling on our programme. Patients with symptomatic AF were invited to participate in an established six-week exercise-based cardiac rehabilitation programme, composed of physical activity and education sessions. At the start of the programme, patients were weighed and measured, performed the six-minute walk test (6MWT), completed the Generalised Anxiety Disorder Questionnaire (GAD-7), and the Patient Health Questionnaire (PHQ-9). Measurements were repeated on completion of the programme. Over two years, 77 patients were invited to join the programme. Twenty-two patients (28.5%) declined participation prior to initial assessment and 22 (28.5%) accepted and attended the initial assessment, but subsequently withdrew from the programme. In total, 33 patients completed the entire programme (63.9 ± 1.7 years, 58% female). On completion, patients covered longer distances during the 6MWT, had lower GAD-7 scores, and lower PHQ-9 scores, compared with their baseline results. Compared with patients that completed the entire programme, those who withdrew from the study had, at baseline, a significantly higher body mass index (BMI), covered a shorter distance during the 6MWT, and had higher PHQ-9 and GAD-7 scores. In conclusion, enrolling patients with AF into an NHS cardiac rehabilitation programme is feasible, with nearly half of those invited completing the programme. In this feasibility study, cardiac rehabilitation resulted in an improved 6MWT, and reduced anxiety and depression levels, in the short term. Severe obesity, higher anxiety and depression levels, and lower initial exercise capacity appear to be barriers to completing exercise-based cardiac rehabilitation. These results warrant further investigation in larger cohorts.
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Mills et al. (2020) conducted an observational in Atrial fibrillation (n=77). Exercise-based cardiac rehabilitation programme vs. Baseline (pre-intervention) was evaluated on 6-minute walk test (6MWT) distance (15% improvement, p=<0.0001). A 6-week exercise-based cardiac rehabilitation programme significantly improved 6-minute walk test distance by 15% (from 389.5 to 447.9 metres, p<0.0001) in patients with atrial fibrillation.
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