Elevated troponin and myocardial infarction in the intensive care unit: a prospective study
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Population
115 consecutive patients admitted to a medical-surgical ICU, mean age 64.1, 53.0% female, Canada. Key…
Design
Cohort, investigators blinded to each other's assessments
Follow-up
ICU and hospital stay
Authors
Discussion
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Implication
MI diagnosis but not troponin elevation alone signals higher ICU mortality risk; extends risk stratification yet leaves open therapeutic implications.
Structured PICO
P
Population
115 consecutive patients admitted to a medical-surgical ICU, mean age 64.1, 53.0% female, Canada. Key inclusion: all consecutive patients admitted to the ICU.
O
Outcome
Frequency of MI and association of elevated troponin and MI with ICU and hospital mortality and length of stayhard clinical
In critically ill patients, a diagnosis of myocardial infarction is an independent predictor of hospital mortality, whereas an isolated elevated troponin without ischemic ECG changes is not.
Limitations
- small sample size
- ECG is not very sensitive for detecting infarction in certain locations (posterior)
- uninterpretable ECGs occur among patients who are pacemaker dependent or have left bundle branch blocks
Cite This Study
Lim et al. (2005) studied this question.
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