Key result
Modifiable metabolic risk factors accounted for a 36.13% population-attributable fraction for incident diabetes and 37.42% for major cardiovascular events.
Why the study?
The individual and combined associations of lifestyle and metabolic factors with new-onset diabetes and major cardiovascular events among Chinese adults aged 40 years or older were undetermined.
Do modifiable lifestyle and metabolic health factors affect the risk of new-onset diabetes and major cardiovascular events in Chinese adults aged ≥40 years?
Population
170,240 participants in China aged ≥40 years
Comparison
Individual and combined lifestyle and metabolic factors
Design
Nationwide, multicenter, prospective cohort study
Follow-up
Up to 5 years
Authors
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May guide prevention efforts in Chinese adults ≥40; extends observational data but leaves causal effects open for trials.
Cohort (n=170,240)
Yes
Do modifiable lifestyle and metabolic health factors affect the risk of new-onset diabetes and major cardiovascular events in Chinese adults aged ≥40 years?
Modifiable lifestyle factors, including physical activity and diet, significantly impact the risk of incident diabetes and major cardiovascular events independently of baseline metabolic status.
Li et al. (2020) conducted a cohort in New-onset diabetes and major cardiovascular events (n=170,240). Modifiable lifestyle and metabolic risk factors was evaluated on New-onset diabetes and major cardiovascular events. Modifiable metabolic risk factors accounted for a 36.13% population-attributable fraction for incident diabetes and 37.42% for major cardiovascular events.
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