What question did this study set out to answer?

To evaluate the prognostic value of the DSM-IV physiological specifier, tolerance, and withdrawal—including withdrawal requiring tremors—in predicting one-year chronicity of alcohol dependence.

January 1, 2000Journal of Studies on Alcohol

Withdrawal and tolerance: prognostic significance in DSM-IV alcohol dependence.

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To evaluate the prognostic value of the DSM-IV physiological specifier, tolerance, and withdrawal—including withdrawal requiring tremors—in predicting one-year chronicity of alcohol dependence.
Assessed household residents (N = 130; 57% men) meeting full criteria for current DSM-IV alcohol dependence at baseline.
Re-interviewed participants after one year using reliable structured diagnostic interviews to determine persistence of alcohol dependence.
Evaluated the DSM-IV physiologic specifier, individual components (tolerance and withdrawal), and an alternative withdrawal definition requiring tremors using chi-square tests and adjusted odds ratios.
The combined DSM-IV physiological specifier (tolerance or withdrawal) did not predict one-year chronicity of alcohol dependence.
Tolerance evaluated independently failed to predict one-year persistence, whereas withdrawal significantly predicted poor outcomes and chronicity.
Requiring tremors as an essential component of the withdrawal syndrome substantially strengthened its predictive power for chronicity.

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Implication

Longitudinal study finds alcohol withdrawal predicts one-year chronicity in alcohol dependence, indicating that specific withdrawal symptoms like tremors have superior prognostic value.

Cite This Study

Hasin et al. (2000) studied this question.

synapsesocial.com/papers/6a8197a5f34fcd4e77776232 https://doi.org/10.15288/jsa.2000.61.431

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Implication

Longitudinal study finds alcohol withdrawal predicts one-year chronicity in alcohol dependence, indicating that specific withdrawal symptoms like tremors have superior prognostic value.

Withdrawal and tolerance: prognostic significance in DSM-IV alcohol dependence.

Key Points

Discussion

Implication

Cite This Study

Withdrawal and tolerance: prognostic significance in DSM-IV alcohol dependence.

Key Points

Discussion

Implication

Cite This Study

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