It is shown here that if we assume that what is conserved in nature is not simply mass-energy, but rather mass-energy plus the energy uncertainty of the uncertainty principle, and if we also assume that position uncertainty is reduced by the formation of relativistic horizons, then the resulting increase of energy uncertainty is close to that needed for a new model for inertial mass (MiHsC, quantised inertia) which has been shown to predict galaxy rotation without dark matter and cosmic acceleration without dark energy. The same principle can also be used to model the inverse square law of gravity, and predicts the mass of the electron.
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