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In vitro study demonstrates dye degradation and antimicrobial and anticancer efficacy of plant-derived CuO-ZnO nanocomposites, indicating significant environmental and therapeutic potential.
In this study, CuO-ZnO nanocomposite was synthesized through an eco-friendly approach using Macroptilium lanthyroides (L.) plant leaves. UV-visible, FT-IRS, XRD, EM-EDX, XPS, DLS, and Zeta potential characterization techniques were used to analyze the synthesized CuO-ZnO NCs. The dye disintegration efficiency of CuO-ZnO NCs was studied under sunlight irradiation, which reduced the dye by 96.2% within 90 min. The zones of inhibition against S. aureus was 18 mm, S. pyogenes was 16 mm, K. pneumoniae was 16 mm, and E. coli was 14 mm, respectively at 30 μg/mL. The antifungal activity of the CuO-ZnO NCs antifungal activity observed against T. viridae was 13 mm, against C. albicans was 12 mm, respectively. CuO-ZnO NCs showed significant antioxidant activity with IC50 = 167.93 µg/mL. The cytotoxic effects of Substantial NCs were observed against the A549 cell line (IC50 = 31.82 µg/mL) and the MCF-7 cell line (IC50 = 38.13 µg/mL).
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P et al. (2026) studied this question.
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