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The study examined glycaemic control and pain perception in patients using NovoPen® 3 with or without PenMate TM , an automatic injection device, in an open, cross‐over trial. Patients (n=57), who had been injecting insulin for at least 12 months and who had been using Novo Pen®3 for at least six weeks prior to the study, were randomised to use Novo Pen®3 with or without Pen Mate TM for six weeks, before crossing over to the alternate system for a further six weeks. Pain perception was recorded night and morning on a 100mm visual analogue scale (VAS). Glycaemic control was monitored by HbA 1c measurements and by 4‐point blood glucose profiles. Pain perception was significantly lower with PenMate TM (p=0.005). No statistical difference in HbA 1c , blood glucose profiles or adverse events were found between the two systems. Patients found PenMate TM easy to use and 84% said they would recommend the device to a person who is uncomfortable with needles.
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Diglas et al. (1999) studied this question.
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