Key result
Sociodemographic, disease-related, and psychological factors, including full-time employment, social support, conscientiousness, and quality of life, significantly predicted flourishing levels in maintenance hemodialysis patients, explaining 56.7% of the variance.
Why the study?
Maintenance hemodialysis patients face substantial psychological challenges, but the factors influencing flourishing—a state of mental well-being and personal growth—remain underexplored.
Cross-Sectional (n=376)
Yes
Flourishing levels among maintenance hemodialysis patients are moderate and are positively influenced by employment, social support, conscientiousness, and quality of life.
Identifies modifiable factors associated with flourishing in hemodialysis; hypothesis-generating, requires prospective validation before clinical use.
Background: Maintenance hemodialysis (MHD) patients face substantial psychological challenges that impacting their overall quality of life. Flourishing, a concept within positive psychology, refers to a state of mental well-being and personal growth. Despite its importance, the factors influencing flourishing in MHD patients remain underexplored. Aim: This cross-sectional study aimed to assess flourishing levels among MHD patients in Shanghai, China, and identify sociodemographic, disease-related, and psychological factors associated with flourishing, with implications for targeted interventions. Method: From October to November 2022, 376 MHD patients across four hospitals completed validated scales measuring flourishing (PERMA Profiler), personality traits (TIPI-C), regulatory emotional self-efficacy (RES), perceived social support (PSSS), and quality of life (EQ-5D). Statistical analyses, including regression analysis, were used to identify factors associated with flourishing. Results: The mean flourishing score was 6.28 ± 1.763, indicating moderate levels compared to general populations. Full-time employment (β = 0.749, p = 0.033), retirement (β = 0.675, p = 0.043), social support from friends/others (β = 0.039, p < 0.001), conscientiousness (β = 0.133, p < 0.001), and better quality of life (β = 1.281, p = 0.001) emerged as significant positive predictors. Conversely, longer dialysis duration (ρ = -0.135, p = 0.009) and higher perceived disease impact (β = -0.084, p = 0.268) were negatively associated with flourishing. Conclusions: The findings highlight the complex interplay between sociodemographic, disease-related, and psychological factors in influencing the flourishing of MHD patients. The level of flourishing in MHD patients' needs to be improved. Developing targeted interventions based on these relevant factors improves quality of life and thus contributes significantly to the well-being of MHD patients.
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Yan et al. (2025) conducted a cross-sectional in End-Stage Renal Disease (ESRD) on maintenance hemodialysis (n=376). Sociodemographic, disease-related, and psychological factors was evaluated on Flourishing score (PERMA Profiler) (adjusted R² = 0.567, p=<0.001). Sociodemographic, disease-related, and psychological factors, including full-time employment, social support, conscientiousness, and quality of life, significantly predicted flourishing levels in maintenance hemodialysis patients, explaining 56.7% of the variance.
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